منابع مشابه
Hormone replacement therapy and breast cancer.
Hormone-replacement therapy (HRT) has been available for many years, but the important question of its place in development and progression of breast cancer remains controversial; provision of reliable risk estimates has been hampered by a lack of controlled data. Observational evidence suggests that the risk of breast cancer may be increased only if HRT is used long term (ie, for longer than 1...
متن کاملHormone replacement therapy and breast cancer
The concern that postmenopausal hormone replacement therapy (HRT) may cause cancer of the breast has lead to an enormous volume of research in epidemiology, endocrinology and tumour cell biology. The epidemiology has become extremely sophisticated because the anticipated effect is small and there are several confounding factors. The consensus today is that long-term HRT (>10 years) is associate...
متن کاملBreast cancer and hormone replacement therapy.
Understanding the association between hormone replacement therapy (HRT), the diagnosis of breast cancer, and the clinical outcome of women who develop breast cancer in the setting of HRT continue to present important challenges for health professionals and the public. The general impression in the medical community is that breast cancer is diagnosed more frequently after prolonged HRT; however,...
متن کاملThe menopause, hormone replacement therapy and breast cancer.
Concern exists that the reduction in breast cancer risk associated with the onset of the menopause will be negated with exposure to hormone replacement therapy (HRT). Evidence from large-scale randomised HRT trials support observational data that have shown a modest increase in breast cancer risk with long-term use (i.e. >15 years) of combined therapy, although this falls following HRT cessatio...
متن کاملHormone Replacement Therapy in the Gynecologic and Breast Cancer Patient.
Hormone replacement therapy has increased in use as a result of its well-established benefits as an effective tool against such consequences as osteoporosis and ischemic heart disease and in the management of menopausal symptoms. However, its possible negative impact on the survival of patients with a previous diagnosis of breast, uterine, or ovarian cancer remains controversial. The risk:benef...
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ژورنال
عنوان ژورنال: BMJ
سال: 2001
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.323.7326.1381